Neurons

Update: This paper has now been published in BMC Biology. “Comprehensive catalog of dendritically localized mRNA isoforms from sub-cellular sequencing of single mouse neurons” Sarah A. Middleton, James Eberwine and Junhyong Kim https://doi.org/10.1101/278648 I selected this article for review for the following reasons: In neurons, RNA localization is a fundamental way to control protein expression. To my knowledge this is the first attempt to map dendritically localized RNAs at single cell resolution The findings reported are very intriguing, in particular the potential role of SINE elements in localization of RNA to dendrites. »