I am a statistical and population geneticist interested in understanding the relationship between DNA sequence variation and complex human disease. To build this understanding, my lab constructs statistical and computational methods grounded in principles of population biology, applying them to genetic data collected across entire human genomes. My research has answered population genetic questions about recent demographic and selective events in human populations, and I have helped to map hundreds of risk loci common diseases, particularly type-2 diabetes and heart attack. I have also contributed to the growing field of causal inference studies via Mendelian Randomization.